研究诚实办公室 (Office of Research Integrity，简称 ORI)为美国一家研究诚实的政府机构。

ORI立定政策及规范来防止并侦察科学研究行为的失当、也提供相关的教育、及调查由美国公共卫生局(USPHS)所支持的在"生物医学"与"行为科学"方面之科学研究行为失当的研究。它并定期的出版ORI本身的研究发现。

ORI为美国公共健康与科技局(OPHS)底下的一个研究机构。

The Office of Research Integrity (ORI) is one of the bodies concerned with research integrity in the United States. It was created when the Office of Scientific Integrity (OSI) in the National Institutes of Health (NIH) and the Office of Scientific Integrity Review (OSIR) in the Office of the Assistant Secretary for Health, Department of Health and Human Services (HHS) merged in May 1992. The Office of Research Integrity oversees and directs Public Health Service (PHS) research integrity activities on behalf of the Secretary of Health and Human Services with the exception of the regulatory research integrity activities of the Food and Drug Administration.