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词汇 Methylmalonic acid
分类 英语词汇 英语翻译词典
释义

Methylmalonic acid

中文百科

甲基丙二酸

甲基丙二酸 (Methylmalonic acid,MMA)是一种二羧酸,是丙二酸的甲基化衍生物,丁二酸(琥珀酸)的同分异构体。

生物体内,甲基丙二酸与辅酶A通过硫酯键结合成甲基丙二酰辅酶A,再通过甲基丙二酰辅酶A变位酶异构化为琥珀酰辅酶A(维生素B12为辅酶),以这种方式进入三羧酸循环,这是有机体回补反应之一。

英语百科

Methylmalonic acid 甲基丙二酸

Methylmalonic acid (MMA) is a dicarboxylic acid that is a C-methylated derivative of malonate.

The coenzyme A linked form of methylmalonic acid, methylmalonyl-CoA, is converted into succinyl-CoA by methylmalonyl-CoA mutase, in a reaction that requires vitamin B12 as a cofactor. In this way, it enters the Krebs cycle, and is thus part of one of the anaplerotic reactions.

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