网站首页  情感咨询  情感美文  情感百科  情感生活  学习充电  旧版美文

请输入您要查询的词汇:

 

词汇 Gitelman syndrome
分类 英语词汇 英语翻译词典
释义

Gitelman syndrome

中文百科

吉特曼氏综合症

吉特曼氏综合症英语:Gitelman syndrome),又称吉特曼症候群 ,是一种常染色体隐性肾脏疾病,其特点是低钙(hypocalciuria)、及低镁(hypomagnesemia)之低钾代谢性碱中毒(Metabolic alkalosis)。它是由位在远曲小管(distal convoluted tubule)的噻嗪类(thiazide)相关钠氯同向转运体(sodium-chloride symporter、亦称为NCC、 NCCT、或TSC)的失活突变(inactivating mutation)所造成的功能丧失。

英语百科

Gitelman syndrome 吉特曼氏综合症

A model of transport mechanisms in the distal convoluted tubule. Sodium-chloride (NaCl) enters the cell via the apical thiazide-sensitive NCC and leaves the cell through the basolateral Cl− channel (ClC-Kb), and the Na+/K+-ATPase. Indicated also are the recently identified magnesium channel TRPM6 in the apical membrane, and a putative Na/Mg exchanger in the basolateral membrane. These transport mechanisms play a role in familial hypokalemia-hypomagnesemia or Gitelman's syndrome.
Gitelman syndrome has an autosomal recessive pattern of inheritance.

Gitelman syndrome is an autosomal recessive kidney disorder characterized by hypokalemic metabolic alkalosis with hypocalciuria, and hypomagnesemia. It is caused by loss of function mutations of the thiazide sensitive sodium-chloride symporter (also known as NCC, NCCT, or TSC) located in the distal convoluted tubule.

随便看

 

依恋情感网英汉例句词典收录3870147条英语例句词条,基本涵盖了全部常用英语单词的释义及例句,是英语学习的有利工具。

 

Copyright © 2004-2024 Yiyi18.com All Rights Reserved
京ICP备2021023879号 更新时间:2025/8/6 19:12:04