抗心律失常药（英语：Antiarrhythmic agents）是一类用于抑制心脏非正常节律（心律不整）的药物，这些情况例如心房颤动、心房扑动、室性心动过速以及心室纤颤。

抗高血压药 · 利尿剂 · 血管舒张剂 · β受体阻断剂 · 钙信道阻断剂 · 肾素-血管紧张素系统（ACE抑制剂、血管紧张素Ⅱ受体拮抗剂、肾素抑制剂）

Antiarrhythmic agents are a group of pharmaceuticals that are used to suppress abnormal rhythms of the heart (cardiac arrhythmias), such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular fibrillation.

Many attempts have been made to classify antiarrhythmic agents. The problem arises from the fact that many of the antiarrhythmic agents have multiple modes of action, making any classification imprecise.