东比利牛斯省（法文：Pyrénées-Orientales、加泰罗尼亚语：Pirineus Orientals）是法国朗格多克-鲁西永-南部-庇里牛斯大区所辖的省份，东邻地中海，南接加泰罗尼亚。该省编号为66。历史上曾为加泰罗尼亚一部分。

Pyrénées-Orientales (French pronunciation: ​[pi.ʁe.ne.ɔ.ʁjɑ̃.tal]; Catalan:Pirineus Orientals; Occitan:Pirenèus Orientals; "Eastern Pyrenees") is a department of southern France adjacent to the northern Spanish frontier and the Mediterranean Sea. It also surrounds the tiny Spanish exclave of Llívia, and thus has two distinct borders with Spain.