Bicine

Bicine is an organic compound used as a buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20 °C. It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone.

Bicine is a contaminant in amine systems used for gas sweetening. It is formed by amine degradation in the presence of O₂, SO₂, H₂S or Thiosulfate.