环球航空（Trans World Airlines，TWA）为美国知名航空公司，总部设于密苏里州的圣路易斯。原名为“跨大陆及西部航空”（Transcontinental and Western Air，T&WA）。T&WA在四十年代和五十年代由霍华德·休斯掌控，在此期间，T&WA一直是最先进客机的积极购买者。在休斯的管理下，T&WA取得了长足进步并更名为环球航空（Trans World Airlines，TWA），在二战后一直与泛美航空瓜分美国国际航线，并且在跨大西洋航线竞争中处于领先地位。TWA于2001年被美国航空并购并结业。

Trans World Airlines (TWA) was a major American airline from 1925 until 2001. It was originally formed as Transcontinental & Western Air to operate a transcontinental route from New York City to Los Angeles via St. Louis and Kansas City. Along with American, United, and Eastern, it was one of the "Big Four" domestic airlines in the United States formed by the Spoils Conference of 1930.