Pendrin

Pendrin, also known as sodium-independent chloride/iodide transporter, is an antiporter anion exchanger protein that in humans is encoded by the SLC26A4 gene (solute carrier family 26, member 4). Pendrin is similar to the Band 3 transport protein found in red blood cells. Pendrin is the protein which is mutated in Pendred syndrome, which is an autosomal recessive disorder characterized by sensorineural hearing loss, goiter and a partial organification problem detectable by a positive perchlorate test.