Levocabastine

Levocabastine (trade name Livostin) is a selective second-generation H₁ receptor antagonists which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis.

As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS₂, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor.