If you have moderate to severe rheumatoid arthritis, month after month, the clock is ticking on irreversible joint damage.

如果你患有中度到重度的类风湿性关节炎，月复一月，不可逆转的关节损伤就会接踵而来。

Having been a former pro-athlete, he had a lot of inflammation and joint damage in his body that began to heal itself and he began to feel better.

作为一名前职业运动员，他的身体有很多炎症和关节损伤，这开始自愈，他开始感觉更好。

Nevertheless, the fda rejected tanezumab in March 2021, owing to risks that its use might desensitise the patients to joint damage and thereby accelerate the spread of their disease.

尽管如此，FDA 还是在 2021 年 3 月拒绝了 tanezumab，因为它的使用可能会使患者对关节损伤不敏感， 从而加速疾病的传播。