When the big retailers open a store, the little guys lose business.大的零售商开店之后,小店便失去了客源。Many immigrants have been highly successful as shopkeepers.许多移民开店做生意都非常成功。My wife decided I should have my own shop.我妻子决定让我自己开店。My latest project is trying to find a site for a shop I want to open.我最近的计划是找个地方开店。