Haploidisation

Haploidisation is the process of halving the chromosomal content of a cell, creating a haploid cell. Within the normal reproductive cycle, haploidisation is one of the major functional consequences of meiosis, the other being a process of chromosomal crossover that mingles the genetic content of the parental chromosomes. Haploidisation commitment is a checkpoint in yeast meiosis that does not occur at 34 C in the temperature-sensitive cdc5-1 mutant strain, which follows the successful completion of premeiotic DNA replication and recombination commitment.