GRAP

GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene.

This gene encodes a member of the GRB2/Sem5 (C. elegans homolog)/Drk (Drosophila homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.

词汇	GRAP
分类	英语词汇英语翻译词典
释义	GRAP 原声例句柯南脱口秀 You start with store-bought crescent roll.you can make the dough from scratch.easy to grap it from the supermarket. 首先用买来的新月卷你也可以自己做面团但是从超市买来方便。 CNN 听力 2013年3月合集 When you have to leave your home quickly like a lot of these refugees have, you may only have time to grap a few things. 当你像很多这些难民们尽可能快的离开自己的家园, 你可能只有短短时间来带走几件东西。英语百科 GRAP GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene. This gene encodes a member of the GRB2/Sem5 (C. elegans homolog)/Drk (Drosophila homolog) family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
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