Lipofuscin
![Micrograph showing lipofuscin, in brown/yellow, in a liver biopsy with ground glass hepatocytes; H&E stain](/Images/godic/202501/14/Ground_glass_hepatocytes_high_mag_cropped2928.jpg")
![Micrograph of heart muscle showing lipofucin pigment, H&E stain](/Images/godic/202501/14/Cardiac_myocyte_showing_lipofuscin_pigment2928.jpg")
Lipofuscin is the name given to finely granular yellow-brown pigment granules composed of lipid-containing residues of lysosomal digestion. It is considered to be one of the aging or "wear-and-tear" pigments, found in the liver, kidney, heart muscle, retina, adrenals, nerve cells, and ganglion cells. It is specifically arranged around the nucleus, and is a type of lipochrome.