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词汇 cyclopamine
分类 英语词汇 英语翻译词典
释义

cyclopamine /saikləu'pæmi:n/

英汉-汉英词典
n. 环杷明
词组 | 习惯用语
您要查找的是不是：
  • encyclopedic adj. 百科全书般的;学识渊博的 百科全书的
  • anticyclone n. 反气旋，反旋风；高气压
  • cyclopean 蛮石 Cyclopean adj. 巨大的，庞大的
  • cyclopedia n. 百科全书
cyclopamine n. 环巴胺；环杷明
原声例句
双语版 TED-Ed 演讲精选

They didn't know exactly how cyclopamine caused the defect but told ranchers to steer clear.

他们并不清楚环杷明是如何导致缺陷的，但告诉牧场工人让羊群避开这种植物。

双语版 TED-Ed 演讲精选

Unfortunately, researchers eventually found that cyclopamine causes negative side effects, and its chemical properties make it difficult to work with.

不幸的是，研究者最终发现，环杷明会导致负面的副作用，并且它的化学性质让人们难以把握。

双语版 TED-Ed 演讲精选

So even though the hedgehog protein is still doing its job of keeping the way clear for smoothened, cyclopamine blocks smoothened from passing along its chemical message.

因此，虽然刺猬蛋白仍在工作，帮助smoothened保持通路顺畅，环杷明阻挡了smoothened通过化学信息传递。

中文百科

环杷明

Head of a lamb born by a sheep that ate leaves of the corn lily plant. The cyclopia in the calf is induced by the cyclopamine present in the plant.

环杷明（环巴胺，11-去氧芥芬胺，英语：Cyclopamine）是自然产生的化学物质，属于甾族的介藜芦生物碱。它是从玉米百合花加州藜芦中分离出的致畸胎剂，可导致独眼畸形（前脑无裂畸形）。

环杷明是以放牧于爱达荷州野生玉米百合花农场的绵羊生下的独眼畸形羊羔命名的。1957年美国农业部的科学家开始了长达11年的研究，最终发现环杷明是导致出生缺陷的罪魁祸首。

英语百科

Cyclopamine 环杷明

Head of a lamb born by a sheep that ate leaves of the corn lily plant. The cyclopia in the calf is induced by the cyclopamine present in the plant.

Cyclopamine (11-deoxojervine) is a naturally occurring chemical that belongs to the group of steroidal jerveratrum alkaloids. It is a teratogen isolated from the corn lily (Veratrum californicum) that causes usually fatal birth defects. It can prevent the fetal brain from dividing into two lobes (holoprosencephaly) and cause the development of a single eye (cyclopia). It does so by inhibiting the hedgehog signaling pathway (Hh). Cyclopamine is useful in studying the role of Hh in normal development, and as a potential treatment for certain cancers in which Hh is overexpressed.

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