The CPE specifically targets the tight junctions that connect epithelial cells lining the intestines to one another.
毒素(CPE)作用于肠上皮细胞之间的紧密连接。
Osmosis-微生物
When the tight junctions get destroyed, it causes inflammation and compromises the structural integrity of the intestinal wall.
一旦上皮细胞的紧密连接被破坏,便会产生炎症反应,损伤小肠壁结构的整体性。
Osmosis-消化
The third section is called the ileum, and it has tight intercellular junctions, allowing it to efficiently absorb fluid and begin concentrating the intestinal contents.
Tight junctions, also known as occluding junctions or zonulae occludentes (singular, zonula occludens), are the closely associated areas of two cells whose membranes join together forming a virtually impermeable barrier to fluid. It is a type of junctional complex present only in vertebrates. The corresponding junctions that occur in invertebrates are septate junctions.