SUMO protein
（重定向自SUMOylation）
![Structure schematic of human SUMO1 protein made with iMol and based on PDB file 1A5R, an NMR structure; the backbone of the protein is represented as a ribbon, highlighting secondary structure; N-terminus in blue, C-terminus in red](/Images/godic/202502/14/HSUMO1_1A5R_nmr_ribbons1213.png")
![The same structure represented with atoms represented as spheres to show the shape of the protein; human SUMO1, PDB file 1A5R](/Images/godic/202502/14/HSUMO1_1A5R_nmr_spheres1213.png")
Small Ubiquitin-like Modifier (or SUMO) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.