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词汇 A form DNA
分类 英语词汇 英语翻译词典
释义

A form DNA

中文百科

A-DNA A-DNA

(重定向自A form DNA)
ADN-A, ADN-B y ADN-Z.
The A-DNA structure.
Side and top view of A-, B-, and Z-DNA conformations.

A-DNA又称A型DNA,为DNA双股螺旋的一种形式,拥有与较普遍的B-DNA相似的右旋结构,但其螺旋较短较紧密。A-DNA是三种具有生物活性的DNA双螺旋结构,另两种则为B-DNA及Z-DNA。一般只有脱水的DNA样本中才会出现,可用来作晶体学实验。此外当DNA与RNA混合配对时,也可能出现A-DNA形式的螺旋。

英语百科

A-DNA A-DNA

(重定向自A form DNA)
The A-DNA structure.
Side and top view of A-, B-, and Z-DNA conformations.
Yellow dots represent the location of the helical axis of A-, B-, and Z-DNA with respect to a Guanine-Cytosine base pair.

A-DNA is one of the possible double helical structures which DNA can adopt. A-DNA is thought to be one of three biologically active double helical structures along with B-DNA and Z-DNA. It is a right-handed double helix fairly similar to the more common B-DNA form, but with a shorter, more compact helical structure whose base pairs are not perpendicular to the helix-axis as in B-DNA. It was discovered by Rosalind Franklin, who also named the A and B forms. She showed that DNA is driven into the A form when under dehydrating conditions. Such conditions are commonly used in to form crystals, and many DNA crystal structures are in the A form. The same helical conformation occurs in double-stranded RNAs, and in DNA-RNA hybrid double helices.

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