Spartanburg is the largest city in and the county seat of Spartanburg County, South Carolina, United States, and the twelfth largest city by population in the state. Spartanburg has a municipal population of 37,013 and an urban population of 180,786 at the 2010 census. The Spartanburg Metropolitan Statistical Area, corresponding to Spartanburg County and Union County had a population of 316,997 as of the 2012 census estimate and Revised Delineations of Metropolitan Statistical Areas.