核黄素激酶




核黄素激酶(英语:riboflavin kinase,EC2.7.1.26)是一个催化以下化学反应的酶:
- ATP + 核黄素
ADP + FMN
该酶催化的反应的底物为ATP和核黄素,产物是ADP和黄素单核苷酸(FMN)。
但是,在古菌核黄素激酶(EC2.7.1.161)中,常使用CTP而非ATP作为反应底物,催化如下反应:
- CTP + 核黄素
CDP + FMN
核黄素激酶也在许多细菌中发现,具有类似的功能,但存在若干数量的氨基酸不同。
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词汇 | Riboflavin kinase |
分类 | 英语词汇 英语翻译词典 |
释义 |
Riboflavin kinase
中文百科
核黄素激酶![]() ![]() ![]() ![]() 核黄素激酶(英语:riboflavin kinase,EC2.7.1.26)是一个催化以下化学反应的酶:
该酶催化的反应的底物为ATP和核黄素,产物是ADP和黄素单核苷酸(FMN)。 但是,在古菌核黄素激酶(EC2.7.1.161)中,常使用CTP而非ATP作为反应底物,催化如下反应:
核黄素激酶也在许多细菌中发现,具有类似的功能,但存在若干数量的氨基酸不同。
英语百科
Riboflavin kinase 核黄素激酶![]() ![]() ![]() ![]() In enzymology, a riboflavin kinase (EC2.7.1.26) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are ATP and riboflavin, whereas its two products are ADP and FMN. Riboflavin is converted into catalytically active cofactors (FAD and FMN) by the actions of riboflavin kinase (EC2.7.1.26), which converts it into FMN, and FAD synthetase (EC2.7.7.2), which adenylates FMN to FAD. Eukaryotes usually have two separate enzymes, while most prokaryotes have a single bifunctional protein that can carry out both catalyses, although exceptions occur in both cases. While eukaryotic monofunctional riboflavin kinase is orthologous to the bifunctional prokaryotic enzyme, the monofunctional FAD synthetase differs from its prokaryotic counterpart, and is instead related to the PAPS-reductase family. The bacterial FAD synthetase that is part of the bifunctional enzyme has remote similarity to nucleotidyl transferases and, hence, it may be involved in the adenylylation reaction of FAD synthetases. |
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