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词汇 Activation potential
分类 英语词汇 英语翻译词典
释义

Activation potential

英语百科

Action potential

As an action potential travels down the axon, there is a change in polarity across the membrane. The Na+ and K+ gated ion channels open and close as the membrane reaches the threshold potential, in response to a signal from another neuron. At the beginning of the action potential, the Na+ channels open and Na+ moves into the axon, causing depolarization. Repolarization occurs when the K+ channels open and K+ moves out of the axon. This creates a change in polarity between the outside of the cell and the inside. The impulse travels down the axon in one direction only, to the axon terminal where it signals other neurons.
Shape of a typical action potential.  The membrane potential remains near a baseline level until at some point in time it abruptly spikes upward and then rapidly falls.
Approximate plot of a typical action potential shows its various phases as the action potential passes a point on a cell membrane.  The membrane potential starts out at -70 mV at time zero.  A stimulus is applied at time = 1 ms, which raises the membrane potential above -55 mV (the threshold potential).  After the stimulus is applied, the membrane potential rapidly rises to a peak potential of +40 mV at time = 2 ms.  Just as quickly, the potential then drops and overshoots to -90 mV at time = 3 ms, and finally the resting potential of -70 mV is reestablished at time = 5 ms.
Action potential propagation along an axon

In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. Neurons play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as "nerve impulses" or "spikes", and the temporal sequence of action potentials generated by a neuron is called its "spike train". A neuron that emits an action potential is often said to "fire".

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