Perafensine
![Skeletal formula of perafensine](/Images/godic/202502/02/Perafensine.svg4210.png")
![Space-filling model of the perafensine molecule](/Images/godic/202502/02/Perafensine_molecule_spacefill4210.png")
Perafensine (INN) (code name HR-459) is a drug which was investigated as an antidepressant but was never marketed. It has been reported to antagonize the effects of reserpine and to inhibit the reuptake of norepinephrine; whether it also affects the reuptake of serotonin or dopamine is unclear.