Metisazone
![Skeletal formula of methisazone](/Images/godic/202501/27/Methisazone3815.png")
![Space-filling model of the methisazone molecule](/Images/godic/202501/27/Methisazone-3D-spacefill3815.png")
![Methisazone synthesis: Bauer, Sadler, Br. J. Pharmacol. 15, 101 (1960); GB 975357 (1964 to Wellcome Foundation).](/Images/godic/202501/27/Methisazone_synthesis.svg3815.png")
Methisazone (USAN) or metisazone (INN) is an antiviral drug that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox.
Methisazone has been described as being used in prophylaxis since at least 1965.