霍霍坎文化（英语： Hohokam Culture）公元前300—公元1400年间的北美印第安人文化，主要位于今美国亚利桑那州中部和南部地区，大体分布于基拉河及盐河的半干旱区域。根据发展先后，分为开创期、拓殖期、定居期和古典期4个阶段。

霍霍坎人居住区的村落由许多分散的个体建筑组成，建筑物用树木、柴枝、胶泥等构成，其下均有地窖，地窖甚浅。种植玉米，辅以野豆及野果采集和狩猎。同时，于基拉河流域建造3英里长的河渠，引河水灌田。此后数千年间，霍霍坎人发展起复杂的灌溉系统，为先哥伦布时期北美洲之最。农田工程也为其伟大成就之一。这一阶段早期，曾发展起几种制陶工艺。

The Hohokam (/hoʊhoʊˈkɑːm/) were an ancient Native American culture centered on the present-day US state of Arizona. The Hohokam are one of the four major cultures of the American Southwest and Northern Mexico in Southwestern archaeology. Considered part of the Oasisamerica tradition, the Hohokam established significant trading centers such as at Snaketown and are considered to be the builders of the original canal system around the Phoenix metropolitan area, which the Mormon pioneers rebuilt when they settled the Lehi area of Mesa near Red Mountain. Variant spellings in current, official usage include Hobokam, Huhugam and Huhukam.