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词汇 HNPCC
分类 英语词汇 英语翻译词典
释义

HNPCC

英语百科

Hereditary nonpolyposis colorectal cancer

(重定向自HNPCC)
 HNPCC is inherited in an autosomal dominant fashion.

Lynch syndrome (HNPCC or hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition that has a high risk of colon cancer as well as other cancers including endometrial cancer (second most common), ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair. It is a type of cancer syndrome.

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