腔肠素（英语：Coelenterazine），是一种萤光素，可发光，存在于七个门的水生生物体内。 是许多荧光素酶和光蛋白的底物。

Coelenterazine is the luciferin, the light-emitting molecule, found in many aquatic organisms across seven phyla. It is the substrate of many luciferases such as Renilla reniformis luciferase (Rluc), Gaussia luciferase (Gluc), and photoproteins, including aequorin, and obelin.