Clavulanic acid
（重定向自Clavulanate）
![](/Images/godic/202501/04/Clavulanic_acid.svg4017.png")
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![The intermediates of the biosynthesis of Clavulanic Acid[3]](/Images/godic/202501/04/Clavualnic_Acid_Biosynthesis4017.png")
![Proposed mechanism of beta-lactam synthetase in the biosynthesis of clavulanic acid.[3]](/Images/godic/202501/04/Beta-lactam_synthetase_mechanism4017.png")
Clavulanic acid (rINN) /ˌklævjuːˈlænᵻk ˈæsᵻd/ is a β-lactam drug that functions as a mechanism-based β-lactamase inhibitor. While not effective by itself as an antibiotic, when combined with penicillin-group antibiotics, it can overcome antibiotic resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins.