Tail of pancreas

The tail of the pancreas, located anatomically left near the hilum of the spleen, is not simply an anatomical distinction. The tail is the only part of the pancreas which contains Pancreatic Polypeptide (PP) cells, which are responsible for secreting pancreatic polypeptide to coordinate exocrine and islet enzyme release. PP cells are found in the tail's periphery. Beta cells (insulin secretory) and delta cells (somatostatin secretory) are found in the central part of the tail as with the rest of the pancreas.