Border cells (Drosophila)
(重定向自Border cells)
The border cells of the fruit fly Drosophila melanogaster are a cluster of 6–8 migratory cells found in the fly's ovary and derived from the follicular epithelium.
Studying cell migration is important from the point of view of metastasis, and for this reason, several model organisms are used to determine what molecules are important in initiating, maintaining and guiding moving cells. Drosophila melanogaster is one of the favorite organisms for studying biological phenomena. The border cells of the Drosophila ovary are a genetically tractable system for studying diverse aspects of moving phenotype. After identifying the genes that are important for this phenotype, their homologs can be investigated for putative roles in turning non-invasive cancerous tumors into metastatic ones.