Santa Rosa, New Mexico
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![The historic Guadalupe County courthouse in Santa Rosa was built in 1909. New wing visible at left.](/Images/godic/202412/21/Santa_Rosa_Courthouse4745.jpg")
Santa Rosa is a city in and the county seat of Guadalupe County, New Mexico, United States. The population was 2,744 at the 2000 census. It lies between Albuquerque and Tucumcari, situated on the Pecos River at the intersection of Interstate 40, U.S. Route 54, and U.S. Route 84. The city is located west of, but not within, the Llano Estacado or "staked plains" of eastern New Mexico and west Texas.