美国劳工联合会-产业工会联合会（American Federation of Labor and Congress of Industrial Organizations，AFL-CIO）是美国最大的工会组织，现有56个国内国际成员组织，会员人数1150万。该组织成立于1955年12月4日，由当时独立的两个工会组织美国劳工联合会和产业工会联合会联合而成。

The American Federation of Labor and Congress of Industrial Organizations (AFL–CIO) is a national trade union center and the largest federation of unions in the United States. It is made up of fifty-six national and international unions, together representing more than 12 million active and retired workers. The AFL–CIO engages in substantial political spending and activism.