Substituted amphetamine
![This shows phenethylamine in blue with its substitution points marked. Amphetamine and its substituted derivatives contain a CH3 group at the alpha-position (Rα).](/Images/godic/202502/13/Phenylethyl_Amine_General_Formula_V1.svg5042.png")
![This shows amphetamine with its substitution points marked, excluding the N-position at the NH2 group which is unmarked.](/Images/godic/202502/13/Amphetamine_numbered.svg5042.png")
Substituted amphetamines are a class of compounds based upon the amphetamine structure; it includes all derivative compounds which are formed by replacing, or substituting, one or more hydrogen atoms in the amphetamine core structure with substituents. The compounds in this class span a variety of pharmacological subclasses, including stimulants, empathogens, and hallucinogens, among others. Examples of substituted amphetamines are amphetamine (itself), methamphetamine, ephedrine, cathinone, phentermine, mephentermine, bupropion, methoxyphenamine, selegiline, amfepramone, pyrovalerone, MDMA (ecstasy), and DOM (STP).