博尼法乔海峡（法语：Bouches de Bonifacio，意大利语：Bocche di Bonifacio）是地中海中的一个海峡。位于法国的科西嘉岛和意大利的撒丁岛两岛之间。宽度大约11公里。博尼法乔海峡也是第勒尼安海和西地中海的分界线。

The Strait of Bonifacio (Corsican:Bucchi di Bunifaziu, Ligurian:Bocche de Bunifazziu, French:Bouches de Bonifacio, Gallurese: Bocchi di Bunifaciu, Italian:Bocche di Bonifacio, Sardinian:Buccas de Bonifatziu) is the strait between Corsica and Sardinia, named after the Corsican town Bonifacio. It is 11 km (6.8 mi) wide and divides the Tyrrhenian Sea from the western Mediterranean Sea. The strait is notorious among sailors for its weather, currents, shoals, and other obstacles.