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词汇 Reciprocal translocation
分类 英语词汇 英语翻译词典
释义

Reciprocal translocation

中文百科

染色体易位 Chromosomal translocation

(重定向自Reciprocal translocation)
4号染色体与20号染色体发生易位的图解。

染色体易位英语:Chromosome translocation,或译染色体对调)是一种染色体异常现象,指非同源染色体的片段重新排列组合。主要可分为两种类型:

另一方面,也可分为:

英语百科

Chromosomal translocation 染色体易位

(重定向自Reciprocal translocation)
Chromosomal reciprocal translocation of the 4th and 20th chromosome.
Overview of some chromosomal translocations involved in different cancers, as well as implicated in some other conditions, e.g. schizophrenia,[9] with chromosomes arranged in standard karyogram order.
Abbreviations:
ALL - Acute lymphoblastic leukemia
AML - Acute myeloid leukemia
CML - Chronic myelogenous leukemia
DFSP - Dermatofibrosarcoma protuberans

In genetics, a chromosome translocation is a chromosome abnormality caused by rearrangement of parts between nonhomologous chromosomes. A gene fusion may be created when the translocation joins two otherwise-separated genes, it is detected on cytogenetics or a karyotype of affected cells. Translocations can be balanced (in an even exchange of material with no genetic information extra or missing, and ideally full functionality) or unbalanced (where the exchange of chromosome material is unequal resulting in extra or missing genes).

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