Qashqadaryo Region (Uzbek:Qashqadaryo viloyati, Қашқадарё вилояти), (old spelling Kashkadarya Region) is one of the regions of Uzbekistan, located in the south-eastern part of the country in the basin of the Qashqadaryo River and on the western slopes of the Pamir-Alay mountains. It borders with Tadjikistan, Turkmenistan, Samarqand Region, Bukhara Region and Surxondaryo Region. It covers an area of 28,400 km². The population is estimated to be around 2,067,000 (2007), with some 73% living in rural areas.