梅亚科（学名：Prunoideae），亦作李亚科或桃亚科（Amygdaloideae），为蔷薇科下的一亚科，下有李属、扁核木属、臀果本属等重要属。

这一类植物的特色，是果实的中心都有一颗外壳坚硬的种子。重要的经济物种有梅、樱桃、杏、桃以及扁桃。

Amygdaloideae is a subfamily within the flowering plant family Rosaceae. It was formerly considered by some authors to be separate from Rosaceae, and the family names Prunaceae and Amygdalaceae have been used. Reanalysis from 2007 has shown that the previous definition of subfamily Spiraeoideae was paraphyletic. To solve this problem, a larger subfamily was defined that includes the former Amygdaloideae, Spiraeoideae, and Maloideae. This subfamily, however, is to be called Amygdaloideae rather than Spiraeoideae under the International Code of Nomenclature for algae, fungi, and plants as updated in 2011.