PRNP
（重定向自Prion protein）
![](/Images/godic/202502/04/Protein_PRNP_PDB_1ag22122.png")
![](/Images/godic/202502/04/PBB_GE_PRNP_201300_s_at_tn2122.png")
![](/Images/godic/202502/04/PBB_GE_PRNP_215707_s_at_tn2122.png")
![Chromosome 20](/Images/godic/202502/04/Location_of_PRNP-gene_in_chromosome_202122.png")
PRNP (PRioN Protein) is the human gene encoding for the major prion protein PrP (for prion protein or protease-resistant protein), also known as CD230 (cluster of differentiation 230). Expression of the protein is most predominant in the nervous system but occurs in many other tissues throughout the body.