4-Hydroxyamphetamine
![Metabolic pathways of amphetamine
4-Hydroxyphenylacetone
Phenylacetone
Benzoic acid
Hippuric acid
Amphetamine
Norephedrine
4-Hydroxyamphetamine
4-Hydroxynorephedrine
Para-Hydroxylation
Para-Hydroxylation
Para-Hydroxylation
Beta-Hydroxylation
Beta-Hydroxylation
OxidativeDeamination
Oxidation
GlycineConjugation
In humans, 4-hydroxyamphetamine is formed from CYP2D6 metabolism of amphetamine; 4-hydroxyamphetamine may subsequently be metabolized by dopamine β-hydroxylase into 4-hydroxynorephedrine.](/Images/godic/202501/31/Amph_Pathway4944.png")
4-Hydroxyamphetamine (4HA), also known as hydroxyamfetamine (INN and BAN), hydroxyamphetamine (USAN), oxamphetamine, norpholedrine, para-hydroxyamphetamine, and α-methyltyramine, is a sympathomimetic drug, that is, a drug that stimulates the sympathetic nervous system.