李德尔氏综合征(Liddle's syndrome、假性醛固酮增多症)是常染色体显性遗传(Dominance (genetics))疾病、特征在于早期频繁严重的高血压，以及与低血浆肾素活性、代谢性碱中毒(metabolic alkalosis)、低钾血症、及垂直相关于低醛固酮水平。

李德尔氏综合征涉及肾功能异常、肾小管的钾损失及钠的过量吸收、与低钠饮食及保钾利尿药(例如，阿米洛利(amiloride))的组合治疗。李德尔氏综合征是非常罕见的，2008年在全球报告中只有不到30个家系或独立病案被发现。

Liddle's syndrome, also called Liddle syndrome and pseudohyperaldosteronism, is a genetic disorder inherited in an autosomal dominant manner that is characterized by early, and frequently severe, high blood pressure associated with low plasma renin activity, metabolic alkalosis, low blood potassium, and normal to low levels of aldosterone. Liddle syndrome involves abnormal kidney function, with excess reabsorption of sodium and loss of potassium from the renal tubule, and is treated with a combination of low sodium diet and potassium-sparing diuretic drugs (e.g., amiloride). It is extremely rare, with fewer than 30 pedigrees or isolated cases having been reported worldwide as of 2008.