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词汇 Leukotriene E4
分类 英语词汇 英语翻译词典
释义

Leukotriene E4

中文百科

白三烯E4

类二十烷酸的合成(右侧为白三烯)

白三烯E4英语:Leukotriene E4)是一种与炎症反应有关的半胱氨酰白三烯类物质,由几种白细胞产生,包括嗜酸性粒细胞、肥大细胞、巨噬细胞和嗜碱性粒细胞,最近还发现了有血小板粘附的中性粒细胞也能产生白三烯E4。

英语百科

Leukotriene E4 白三烯E4

Eicosanoid synthesis (leukotrienes at right)

Leukotriene E4 (LTE4) is a cysteinyl leukotriene involved in inflammation. It is known to be produced by several types of white blood cells, including eosinophils, mast cells, tissue macrophages, and basophils, and recently was also found to be produced by platelets adhering to neutrophils. It is formed from the sequential conversion of LTC4 to LTD4 and then to LTE4, which is the final and most stable cysteinyl leukotriene. Compared to the short half lives of LTC4 and LTD4, LTE4 is relatively stable and accumulates in breath condensation, in plasma, and in urine, making it the dominant cysteinyl leukotriene detected in biologic fluids. Therefore, measurements of LTE4, especially in the urine, are commonly monitored in clinical research studies.

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