Lastly, an iron molecule is added to a protoporphyrin IX via the enzyme ferrochelatase.
最后,铁分子通过亚铁螯合酶添加到原卟啉IX中。
Osmosis-血液肿瘤
Lead poisoning has also been shown to denature enzymes important in heme synthesis, like Delta aminolevulinate dehydratase and ferrochelatase, which are important for heme synthesis.
Ferrochelatase is an enzyme that is encoded by the FECH gene in humans. Ferrochelatase catalyses the terminal (eighth) step in the biosynthesis of heme, converting protoporphyrin IX into heme B. It catalyses the reaction: