Medial longitudinal fasciculus

The medial longitudinal fasciculus (MLF) is one of a pair of crossed fiber tracts (group of axons), on each side of the brainstem. These bundles of axons are situated near the midline of the brainstem and are composed of both ascending and descending fibers that arise from a number of sources and terminate in different areas. MLF is the main central connection for the oculomotor nerve, trochlear nerve, and abducens nerve. The vertical gaze center is at the rostral interstitial nucleus (riMLF).