Research suggests that beta-amyloid proteins that accumulate in the brain of Alzheimer's patients may cause abnormal rise in extrasynaptic glutamate levels by inhibiting glutamate uptake or triggering glutamate release from glial cells.

研究表明，在老年痴呆症患者的大脑中积累的β淀粉样蛋白患者可能通过抑制谷氨酸摄取导致突触外谷氨酸水平异常升高或者触发胶质细胞释放谷氨酸盐。