C0t analysis
![Repetitive DNA sequences renature at lower C0t values than single-copy sequences.](/Images/godic/202501/06/CoT_analysis0237.png")
C0t analysis, a technique based on the principles of DNA reassociation kinetics, is a biochemical technique that measures how much repetitive DNA is in a DNA sample such as a genome. It is used to study genome structure and organization and has also been used to simplify the sequencing of genomes that contain large amounts of repetitive sequence.