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Buddy, don't close yourself off from new things.
哥们儿 不要拒绝新鲜事物。
We can’t close ourselves off from those opportunities.
我们不能将自己隔绝在这些机遇之外。
You could be really closed off, hard.
你也会封闭自己 冷酷无情。
Roads to the prison have been closed off.
通往这座监狱的道路已被封锁。
So Hawaii was still closed off.
所以夏威夷仍然是封闭的。
Soon after, his throat closed off.
很快,他的嗓子就堵住了。
The barrier island was closed off Thursday as the storm approached.
周四,由于风暴来袭,这座堰洲岛被封锁。
A true artist doesn't close themselves off to new experiences.
真正的艺术家不会阻止自己尝试新体验。
But the town has effectively been closed off from the outside world.
但该镇实际上已与外界隔绝。
This will help thicken their skin and close off any small cuts.
这将有助于土豆皮变厚以及封闭土豆任何小的破损处。
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