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词汇 Chromatin bridge
分类 英语词汇 英语翻译词典
释义

Chromatin bridge

英语百科

Chromatin bridge

A.
A. Microtubules localized at a chromatin bridge. These polymers are stained with anti-tubulin antibody and viewed using fluorescence microscopy. B. Merged images of two daughter cells connected by a chromatin bridge. The fluorescence techniques of indirect immunofluorescence and DAPI staining were utilized. C. The same cells visualized using DAPI staining.
A chromatin bridge, visualized using DAPI staining.

Chromatin bridge is a mitotic occurrence that forms when telomeres of sister chromatids fuse together and fail to completely segregate into their respective daughter cells. Because this event is most prevalent during anaphase, the term anaphase bridge is often used as a substitute. After the formation of individual daughter cells, the DNA bridge connecting homologous chromosomes remains fixed. As the daughter cells exit mitosis and re-enter interphase, the chromatin bridge becomes known as an interphase bridge. These phenomenon are usually visualized using the laboratory techniques of staining and fluorescence microscopy.

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