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词汇 Bisphosphonate
分类 英语词汇 英语翻译词典
释义

Bisphosphonate

原声例句
Osmosis-肌骨

Treatment for osteoporosis usually relies on bisphosphonate drugs like alendronate and risedronate.

骨质疏松的治疗通常依赖于双膦酸盐类药物,例如阿仑唑奈、利塞膦酸盐。

英语百科

Bisphosphonate

Chemical structure of pyrophosphate (A, above) and bisphosphonates (B, below). P = phosphorus, O = oxygen, H = hydrogen, C = carbon, R = side chain. In bisphosphonates, the central oxygen atom is replaced with a carbon atom.  All bisphosphonates share a common phosphorus-carbon-phosphorus motif with two side chains (R1 and R2 in the figure).  The R2 side chain determines the chemical properties of the drug, and distinguishes individual types of bisphosphonates.  This chemical structure affords a high affinity for calcium hydroxyapatite, allowing for rapid and specific skeletal targeting.
HMG-CoA reductase pathway

Bisphosphonates are a class of drugs that prevent the loss of bone mass, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. They are called bisphosphonates because they have two phosphonate (PO(OH)
2
) groups.

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