Tangier disease
（重定向自Alpha High Density Lipoprotein Deficiency Disease）
![Diffuse hazy opacity of the right cornea in a patient with Tangier disease.](/Images/godic/202412/20/Tanger0012.gif")
![Tangier disease has an autosomal recessive pattern of inheritance.](/Images/godic/202412/20/Autorecessive.svg0012.png")
Tangier disease (also known as Familial alpha-lipoprotein deficiency) or Hypoalphalipoproteinemia is a rare inherited disorder characterized by a severe reduction in the amount of high density lipoprotein (HDL), often referred to as "good cholesterol," in the bloodstream.