1. Pyridazinone derivatives have considerable kinds of biological activities such as those cardiotonic,platelet aggregation inhibitory,anti-inflammatory,aldose reductase inhibitory,antifungal and so on.
   哒嗪酮类化合物具有多种重要的生物活性,根据作用机制的不同,可分为钙增敏剂、磷酸二酯酶抑制剂、环氧合酶抑制剂等,并可用于相关疾病的治疗。
2. The synthesis of epalrestat,an aldose reductase inhibitor, was improved. The yield of its intermediate 3-carboxymethyl rhodanine was raised to 76.4%.
   对醛搪还原酶抑制剂依帕司他的合成工艺作了改进，使中间体绕丹宁乙酸的收率提高到76．4％。
3. Transketolase is the key enzyme of pentose-phophate pathway, catalyses transfer of a two-carbon fragment from a ketolase (donor substance) to an aldose (acceptor substance).
   摘要转酮醇酶是磷酸戊糖途径的关键酶，催化二碳单元在酮糖（供体）和醛糖（受体）间的转移。

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