蟾酥，亦称蟾毒素，是中药材攻毒杀虫止痒药的一种，该药材出自于《药性论》一书，有解毒止痛的功效。蟾酥为蟾蜍科动物中华大蟾蜍（Bufo gargarizans Cantor）或黑眶蟾蜍（Duttaphrynus melanostictus Schneider）的耳后腺和皮肤腺体的干燥分泌物，，蟾酥的药性辛、温，有小毒；入心经。

蟾酥主要产于吉林、山东、辽宁、江苏等地，主要采收于夏秋两季。一般采收将捕获的蟾蜍洗净，挤取耳后腺及皮肤腺的白色浆液，然后瓷器承装，在采收的过程忌用铁器，以免将白色浆液变黑。

Bufotoxins are a family of toxic steroid lactones found in the parotoid glands, skin and venom of many toads (genus Bufo); other amphibians; and some plants and mushrooms. The exact composition varies greatly with the specific source of the toxin. It can contain: 5-MeO-DMT, bufagins, bufalin, bufotalin, bufotenin, bufothionine, epinephrine, norepinephrine, and serotonin. The term bufotoxin can also be used specifically to describe the conjugate of a bufagin with suberylargine.